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has shown that the administration of 600 mg/day of sulbutiamine for 8 weeks significantly decreased social inhibition associated with the depressive event [35]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Cryan J.F., ORiordan K.J., Cowan C.S.M., Sandhu K.V., Bastiaanssen T.F.S., Boehme M., Codagnone M.G., Cussotto S., Fulling C., Golubeva A.V., et al

This aggregation mechanism may in fact even play a role in the aggregation of more unstable SOD1 mutants, compounding aggregation originating from immature misfolded apo metalloforms